ABSTRACT

Abundant adverse effects following the administration of synthetic drugs mainly in the case of chronic diseases have led the human life to a faceless threat for a healthy lifestyle. Medicaments from herbal sources have emerges as a safe choice and a better alternative. History of herbal drugs in the health care system is almost as old as human civilization and herbs more than thousand in numbers have been listed under the traditional system for treatment of various cardiovascular problems. Many of these plants have been found to provide desired pharmacological actions but their clinical use is very less due to their low bioavailability and other related profiles. According to WHO about 80% of the population still believe that drugs from natural sources has potential for advancement on clinical platform. Nanotechnology bears much hope for the development of many of these poor bioavailable herbal drugs. Converting herbal drugs to the nanoscale delivery system using various fabrication approaches can result in the improvement of many pharmacokinetic profiles as well as in vivo stability and controlled absorption of the drug at the desired site. Aim of the present review is to focus on many facts related to cardiovascular diseases (CVDs) and the role of herbal drugs in treatment with nanotechnology driven delivery system.