ABSTRACT

Exercise-induced oxidative stress is manifested by a rise in peripheral and intracellular measures of DNA, lipid and protein damage. To the contrary, exercise-induced oxidative eustress provokes a beneficial intracellular response, where skeletal muscle adaptation such as an upregulation in endogenous antioxidant enzymes ensues. Free radical and non-radical species collectively termed reactive oxygen species (ROS) generated by a fixed exercise intensity and duration are central to oxidative (eu)stress. This chapter will (1) briefly introduce ROS and (2) provide an overview of the key exercise-induced oxidative (eu)stress literature.