ABSTRACT
Pregnancies in women with Turner syndrome are recognized as having an increased risk of complications, with an increased rate of pregnancy loss and of severe obstetric complications. The most dangerous complication includes aortic dissection, which is associated with maternal death during pregnancy or postpartum in as high as 2% of the cases.
As a substantial proportion of women with Turner syndrome may require assisted reproductive technology treatments to achieve pregnancy, either with their own or donated oocytes, it is important that the treating teams are aware of these specific risks. Additionally, a large population of patients with a Turner karyotype would present with reduced ovarian reserve for their age, and they may also wish to undergo fertility preservation. For all cases, a complete cardiovascular screening to evaluate the safety of a future pregnancy should be completed and the patients counseled accordingly.
