This chapter presents the possibility of implantable biomedical devices (IMD) in the ongoing years. Various people all over the world are presently relying upon implantable devices to improve their health. An implantable antenna for biomedical applications is a key part of a transmitter. Implantable biomedical antennas are widely utilized and most fitting as an alternative to the intricate medical services. Implantable biomedical antennas are utilized for the people and as well as for the animals. The implantable biomedical antennas are utilized for constant checking of body temperature and blood pressure, tracking the dependent individuals or lost pets, and exchanging health records remotely from the implanted antenna in the human body, for example, pacemaker to an outside radio frequency receiver. As such, watching patients distantly can be recognized without having any direct physical contact. Biomedical telecommunication allows the exchange of information from “on-body to off-body,” or from “on-body to on-body,” or from “in body to off-body.” The motivations behind implantable biomedical antennas are remote health checking, ailment treatment, stomach-related observing, hyperthermia, and finding the area of the tumor. The difficulties looked by utilizing these implantable antennas comprises of the design and implantation of these antennas in the human body because the human body is lossy. While structuring the implantable antenna, the accompanying parameters should be viewed as like conservative size, significantly less weight, safety, and successful work inside the medical frequency band (industrial, scientific, and medical 20(ISM) radio bands, medical implant communication services (MICS), and so on), wide working bandwidth and high radiation efficiency for ease and comfort of the patients. The main theme of this chapter is to present the design and difficulties of different sorts of implanted antennas. Additionally, simulation and measurement methods and results of implanted antennas are studied. Moreover, this chapter gives an overview of biocompatibility and safety issues.