ABSTRACT

Biological surfactants (biosurfactants) are chemical compoundsdiverse with structural variety produced by microbiota. Lipopeptide biosurfactants (LPs) have been attracted the attention of researchers due to their considerable industrial value as their exceptionaltenside activity incombination with their biocompatibility makes them appealing for numerous applications. Lipopeptide familyof biosurfactants are significant for the pharmaceutical industry due to their intrinsic antibiotic characteristics. The high frequency of lipopeptide (LP) production in common soil microorganisms in combination with structural diversity of the synthesized biosurfactants has created an abundant natural pool of compounds with potentially interesting properties. Unfortunately, the bioactivity of lipopetides against pathogenic microorganisms is often associated with riskyside effects that restrict on medically relevant applications. The accumulatedknowledge of lipopetide biosynthesis and their frequent structural variations caused by natural genetic rearrangements has therefore interested various approaches in order to operate biosurfactant composition and production mechanisms. This chapter will give an overview on current discuss chemical structure andbiosynthesis of lipopeptides came from different microbiological groups and the related industrial applications.