ABSTRACT
We report on the application of the biospeckle laser method (BLM) to test drug effects on Trypanosoma cruzi (T. cruzi) parasites. The method, enabled to assess the activity of parasites under different drug concentrations, thus demonstrating the effectiveness of the proposed methodology. The spatial-temporal correlation and speckle grain size were measured in order to assess the immediate action of the drug on parasites. The achieved results allowed the validation of the methodology as a fast and non-invasive for testing the effectiveness of Epirubicin on T. cruzi parasites. The proposed methodology was also validated by other well-known digital processing approaches.
