ABSTRACT
The proliferation of T lymphocytes is stimulated by allogeneic and autologous non-T lymphocytes (1), This reaction is termed the mixedlymphocyte reaction (MLR). The allogeneic MLR serves as an in vitro model of allograft rejections. The autologous MLR generates helper (2), suppressor (3), and cytotoxic activity (4) and may play an immunoregulatorv role in vivo.
