ABSTRACT

The advent of synthetic sweeteners such as saccharin, cyclamate, and more recently aspartame has made it possible to offer people sweet taste in their diet without the calories that a diet high in sucrose often implies. However, stringent government regulations about food additives shown to be carcinogenic in animals have led to the withdrawal of Food and Drug Administration approval for food use of cyclamate and a potential ban on the use of saccharin. For any food additive there needs to be an assessment of benefits weighed against the potential risks from the use of such compounds. One group who would stand to benefit by the availability of low-calorie food analogs are obese people. Animals were adapted to the base-line liquid diet for thirty days before the actual dilution experiment began. The dilution experiment was divided into five ten day experimental periods.