ABSTRACT

Although antibiotics and related compounds have been known for only the past four decades, there has been tremendous activity in the area of the analysis of their preparations, residues, and metabolites, presumably due to the medical and economic significance of these materials. Consequently, as gas chromatography (GC) came on the scene as a practical tool of analytical chemistry, soon after the advent of the penicillins, its capabilities to impart qualitative and quantitative insight into the composition of antibiotic preparations and related materials were immediately utilized.