ABSTRACT
Several investigators have studied the cariostatic properties of tin in diets, dentifrices, and mouthwashes. Tin is widely distributed in plant and animal materials. Food additives are also only a minor source of dietary tin. Although the absorption and overall apparent retention of tin by human subjects in balance studies is low, tin has been found in at least trace amounts in most mammalian tissues. A variety of organic tin compounds are used commercially; a number are extremely toxic. The toxicity of these compounds is dependent upon the organic constituents of the tin compounds, the manner of exposure, and the animal species studied. Most foods contain some aluminum. Estimates of the aluminum content of any biological sample should be viewed with skepticism. A great deal has been published in the popular press on the toxicity of aluminum.
