ABSTRACT

As the field of electrochemical biosensors expands, there may be many applications for monitoring bioprocesses. A promising development uses flow injection analysis, where a very small sample (for example, 5 microliter) of the reaction broth is automatically and periodically fed into a flowing stream and monitored with a biosensor. There are three types of electrochemical sensors categorized by the mode of measurement: amperometric, potentiometric, and conductometric. There are several key advantages to electrochemical biosensors that make them very useful in bioprocess control. One of them is, electrochemical biosensors are inexpensive, relatively simple in theory and operation and are adaptable to process control instrumentation.