ABSTRACT
The management of many adult and childhood tumors has been transformed in recent years. Part of this change has derived from improved accuracy of diagnosis which has allowed the more appropriate tailoring of therapeutic regimens. Consequently, the effectiveness of radiotherapy and combinations of potent chemotherapeutic agents has been enhanced while their concomitant toxicity has been minimized. As a result, the prognosis of many tumors has been improved and the quality of life of the patients bearing them enhanced.
