ABSTRACT

A retrospective review of the Toxin Clinic database was carried out over an 18 year period, identifying patients with esotropia under 20 prism dioptres. Sixty eight patients with esotropia of 20 prism dioptres or less were treated with Botulinum Toxin. There 47 females and 21 males, with a mean age of 34 years (range 11–78). Thirty two (47%) patients had residual esotropia, 20 (29%) had primary esotropia, 11 (16%) had consecutive esotropia, 4 (6%) had secondary esotropia and 1 (1.5%) had a decompensating esophoria. The mean pre toxin angle was 16 prism dioptres (range 6–20). Four hundred and thirty four injections were given, with an average of 6 per patient (range 1–36). Forty five (66%) patients underwent continued toxin treatment with an interval of 3 to 31 months. Thirteen (19%) patients achieved long term benefit from only one injection. Seven were unable to demonstrate binocular vision pre injection but demonstrated it post injection. Following an initial injection 9 (13%) patients proceeded to surgery. Botulinum Toxin is a successful treatment for these patients.