The field of “green electronics” is a cross-disciplinary research area which recognises naturally occurring or nature-inspired compounds and use them for the design and synthesis of eco-friendly synthetic-organic materials that are environmentally safe biodegradable/or biocompatible, for making of “Green-Devices.” The actual goal of this research field is to produce environmentally viable semiconducting materials and their applications in devices such as organic electronics to carry low energy intensity, low cost, negligible waste production, and also accomplish good functionalities. This chapter briefly reviews major research work based on ideologies of green chemistry in the synthetic strategies in making of semiconducting materials including small molecules and polymers or nature-inspired biocompatible materials and their applications in organic-green electronics.