ABSTRACT
For centuries, people have used enzymes and other compounds produced by several model organisms, like microorganisms, plants, and animals, to obtain biotechnological products. The production of enzymes and different products of commercial interest can be obtained through the genetic manipulation of the metabolic pathways. The products obtained by the catabolic regulation of the metabolism of these microorganisms are widely applied in the industry for the production of food, beverages, drugs, animal feed, personal hygiene, products, pulp and paper, diagnosis, and therapy. This chapter describes the advances made in the genetic manipulation for catabolic regulation for the accumulation of commercial interest products in bacteria.
