ABSTRACT

Nanotechnology is a multidisciplinary technological area in perpetual development, and their applications in biomedical field as nanovectors, nanoparticles (NPs), or nanosensors can be associated with biomolecules. Multipurpose sensors are designed to identify different pathological parameters, foreign proteins/antigens, and toxic compounds in a quicker and more sensitive manner. This paper focuses on NPs for diagnostic, screening, and identification of infectious diseases, enhances clinical diagnosis, and is used for early-stage prophylactic disease diagnosis. Thus, NPs provide improved comparison, controlled biodistribution, and multimodal imaging in the area of medical radiology. Imaging agents are currently being produced using different nanomaterials due to their special optical, chemical, and physical properties. Many categories of NPs may be used as extremely sensitive fluorescent probes and biosensors for the diagnosis of very small lesions that cannot be identified by traditional imaging agents or for the production of molecular systems/devices as nanomarkers. The assessment of nanomolecular diagnostics in medicine and the creation of detailed guidance documents allow for the safety evaluation of nanomolecular diagnostics in medicine, but more study in nanotoxicology is required.