ABSTRACT
This chapter describes the use of various nanomaterials as a heterogeneous catalyst, which are efficient and modular routes for the preparation of useful seven-membered heterocyclic intermediates in drug discovery and development. Heterocyclic motifs demonstrate noteworthy chemistry with important applications in medicinal, organic chemistry, pharmaceuticals, and related industries. Benzazepines, which are seven-membered azaheterocyclic fused aromatic ring motifs, has received more attention due to their broad range of biological activity and are used as building blocks in the synthesis of various natural products, drug discovery, and developments. Benzodiazepines (BZDs) represent one of the important and highly explored classes of seven-membered aromatic heterocycles that contain a two-ring N that are critical for numerous applications in the pharmaceutical industry and the organic synthesis of complex molecules. BZD and its derivatives have been successfully employed in the treatment of various psychotic disorders, infections, and microbial infections that are caused by resistant bacteria.
