ABSTRACT

This chapter describes nanocatalyst and their application in the organic transformation of biological activated heterocyclic compounds, such as pyrrole, indole, furan, and benzofuran derivatives. The advantages of nanocatalysts are the required small quantity, decreased size of the nanocatalyst, more surface area, exposure to the reactant, and non-toxic. Using a nanocatalyst, a minimum time is required for the formation of the desired product. The chemistry of pyrroles heterocyclic compounds are more reactive at the second carbon atom. The pyrrole derivatives have new structures and exhibit a broad range of biological activities. The high catalytic potential of nanocatalysts is recovery, and the recycling of expensive nanocatalysts is an important process in modern nanocatalysts. Furan is a significant heterocyclic compound that exhibits outstanding biological activities during the synthesis of natural products. Nanocatalysts have gained significant attention due to their high reactivity, low cost, and they are non-toxic and can be applied in coupling reactions.