ABSTRACT
Diabetes is a devastating metabolic disorder causing socioeconomic concerns. Extensive research studies on bioactive molecules for their pharmacological significance have been attempted. Gymnema sylvestre R. Br. (Hindi: gurmar) has been studied for its triterpenoids (known as Gymnemic acids analogs) and polypeptide Gurmarin, which is gaining immense popularity as herbal medication for treatment of Type-II diabetes. The herb exhibits physiological properties ranging from regulation of blood sugar levels, control sugar cravings, and regeneration of pancreas. This chapter provides a comprehensive insight on the significance of triterpenoids from G. sylvestre R. Br., their potential mechanism of action in the treatment of diabetes, and its prospects and challenges in diabetes therapy.
