ABSTRACT
Two-dimensional (2D) nanomaterials with planar structures exhibit the largest specific surface areas among nanomaterials. Due to this property, they are suitable candidates to carry different payloads (drugs, cells, genes, proteins, optical probes, etc.) in drug delivery systems. In addition, depending on their chemical composition, they exhibit a wide spectrum of characteristics such as conductivities, surface charges, and functionalities, which enables them to be applied in fabrication of biomaterials with finely tuned characteristics. Moreover, some 2D nanomaterials have shown good biocompatibility and biodegradability. Inspired by these features, this chapter highlights the promise of various 2D nanomaterials as vehicles in different aspects of regenerative medicine (i.e. tissue regeneration, cell therapy, gene therapy, etc.). Related studies have implicated that the application of 2D nanomaterials may benefit the field of regenerative medicine with better treatment options. Clays, layered double hydroxides, graphene, black phosphorous, and MOFs are among the numerous 2D nanomaterials that have been covered in this chapter.
