ABSTRACT
Tissue engineering is an emerging multidisciplinary field that focuses on the development of biological substitutes that can replace, restore, maintain, or enhance tissues functionality. Tissue replacement and its performance depend on the temporal and spatial control over biological events mediated by cascades of intracellular signalling. In this context, progress in nanoparticle production with low toxicity, potential with targeted response delivery, and exact control over nanoscale systems have enabled their use in improved tissue regeneration. In last several decades, significant research has been carried out in tissue engineering,which has hinted at much promise. Nanotechnology, which made use of materials with size less than 100 nm with the potential ability to mimic the surface properties of natural tissues,is still in need to furnish exciting alternative materials to eventuallyresolve thenumerous problems related toconventional implants. For these reasons, over the last decade, a lot of attention has been given towards the use of nanoparticles as promising candidates for their use in the distribution of various growth factors, for imparting contrast for imaging and for controlling characteristics of the implants and/or scaffolds. However, the application of nanoparticles to tissue engineering is a wide issue and in this short chapter, we only focus on aspects of nanoparticles relevant to bioceramic. We view the development of various kinds of bioceramic nanoparticles and their characteristics,especially, the recent research on the fabrication of bioceramic nanoparticles and their use in scaffold preparation for tissue engineering targeting at bringing out specific cellular reaction. Moreover, at last, as an important future area of research, we specifically emphasise about the application of bioceramic nanoparticles in different tissue engineering fields and their use related to human health.
