ABSTRACT

Ceramic nanoparticles (NPs) are nanosized carriers which are globule shaped. These comprise of a hydroxyapatite core, whose surface is non-covalently altered by oligosaccharide, onto which the drug of interest are further adsorbed on the surface. These ceramic NPs are also referred to as “aquasomes.” Aquasomes are triple-layered self-assembled nanoparticulate drug delivery systems, which are used for the successful delivery of drugs without compromising with their conformational integrity. They establish a non-covalent link with various molecules which further promote more stability as compared to liposomes and other NPs. In the present chapter, various aspects of aquasomes are discussed such as properties, method of preparation, characterization, and various application in drug delivery.