ABSTRACT

Due to the noncontact, precise, reproducible, and efficient characteristics, laser processing technique has been becoming an attractive tool in biomedical applications. As one of the typical tools of biomedical applications, laser surgery shows high potential in orthopedic surgery, eye surgery, and so on. Meanwhile, as another typical biomedical application, laser modification of biomaterials is widely considered to be an effective way to control biomedical properties of surfaces such as cell behaviors. It highlights the unique advantages including non-pollution, low cost with high reproducibility and uniformity, high enhancement factor, and capability to tailor topography at the micro- and nanoscale. Nevertheless, for practical biomedical applications, the requirements of laser processing with complex processing environments and objects, large dynamic range, high efficiency, and high precision are becoming more and more urgent. Moreover, the on-line monitoring of laser processing is an important solution. Furthermore, with the further combination of collaborative monitoring and artificial intelligence, the intellectualization and high efficiency of laser processing and its on-line monitoring will be promoted.