ABSTRACT
Today, 2D material-based sensor devices have been deliberately extensive for various biosensor applications like DNA hybridization for genetic disease detection, pH identification, glucose sensor, and cancer detection. The present chapter is focused on the different types of fabrication methods and characterizations of biosensor devices and their ambipolar behavior to detect the biomolecules. Presently, 2D-based electronic devices are known for attractive peculiarities, like the quantum hall effect, tunneling effect, and many other transport properties owing to their carrier density and polarity, as well as high charge mobility for electrons and holes. Chemical Vapor Deposition (CVD) and mechanical exfoliation methods are the most familiar methods to develop the 2D material-based devices fabricated on the SiO2 substrate. Based on the electrical property, the sensor devices were executed in advanced applications, namely DNA hybridization detection, pH sensors, and protein detection. The 2D material-based devices provide good diagnostic methods for cancer detection and can help mRNA detection. The sensitivity of the device was estimated at the device performance. These generous detections will also provide a platform for the effective detection of cancer therapy. Fabrication of this kind of compact biosensor device enables low-cost, real-time sensitive amperometric sensors, which enhance the effective sensing and user-friendly platform of biosensing applications.
