ABSTRACT
In immunocompetent individuals, SARS-CoV-2 infection leads to hypercytokinemia, an unregulated hyperinflammatory response that results from the systemic spread of a localized inflammatory response to viral or bacterial infection. In December 2019, a cluster of communicable severe acute respiratory illness cases caused by a novel Coronavirus was reported for the first time in the Hubei province of China. The shedding of viral particles begins ~two to three days before the onset of symptoms until five days after the appearance of symptoms. The infected individual may be completely symptomatic or may show serious clinical symptoms. Patients have fever, cough, myalgia, headache, anosmia, dysgeusia, and diarrhea. Severe patients may present with COVID pneumonia with hypoxia and thrombotic episodes. Thrombosis refers to the formation of blood clots inside a blood vessel; the clot formed is termed a thrombus. Thrombus prevents the normal circulation of blood to concerned organs.
