ABSTRACT
This review article is focused on the roles of nucleotide sequence analysis in human genetics and genomics. Nucleotide sequence involves subjecting RNA, Protein and DNA sequences to analytical methods in order to elucidate their features, function, structure or evolution. Some of these methods include sequence alignment and database searches. Analysis of the human genome has revealed a high percentage similarity between humans from different races across the globe. They are also equal in their capacity for development that is determined by socio-historic conditions and not necessarily genetics. The human genome contains all necessary the information for the growth and survival of the human species. The size of a genome copy that is encompassed in all the body cells is approximately three billion DNA base pairs. Generally, the analysis of the human DNA sequences (coding and non-coding) plays a major role in current clinical practice in disease diagnosis and possible treatments. Therefore, nucleotide sequence analysis offers fundamental insights towards advancing human genetics and genomics.
