ABSTRACT
Metal-organic frameworks (MOFs) are highly porous materials that have attracted enormous attention in recent years owing to their fascinating structures and widespread potential applications. In this chapter, the recent developments of MOF-based materials for advanced electrochemical sensing of pharmaceutical compounds are systematically summarized. A detailed discussion about the structural-property relationship and the different strategies used for the rational design and controllable synthesis of versatile MOF-based materials based on the specific requirements of the final electrochemical sensing applications are outlined. Further, it covers the detection of pharmaceutical compounds using MOF-based electrochemical systems. This chapter includes the compounds used in pharmaceutical processes and by-products which are considered as wastes. Further, it also covers drugs that are electro-active, in other words, which undergo oxidation and reduction as well as the compounds which do not undergo oxidation or reduction, namely, electro-inactive compounds. Finally, this chapter concludes with the advancements in the technology carried out in the field and also the challenges and opportunities of developing MOF-based materials as novel electrochemical sensing platforms.
