ABSTRACT

Endocrine-disrupting compounds (EDC) are exogenous chemicals or mixtures of chemicals which can exert a significant effect on the endocrine system. From a global perspective, the pollution of EDC is a serious environmental problem and a global public concern nowadays. Therefore, it is of great significance for the development of high-sensitivity and high-selectivity EDC detection methods. As an emerging detection method, MOF-based electrochemical sensors could provide a unique alternative detection method for EDC detection. The application of MOFs in the construction of electrochemical sensing platforms could enhance the performance of electrochemical sensors by improving electrical conductivity, offering more binding sites, and providing more electrocatalytic sites. With the continuous research on the synthesis and optimization of MOFs for electrochemical detection, electrochemical sensors based on MOFs are moving towards the practical application of EDC detection. In this chapter, the definition and classification, hazards, and detection status of EDCs are described and summarized. The representative research on the development of MOF-based electrochemical sensors for EDC detection is reviewed in detail.