ABSTRACT

Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful techniques available for studying the structure of molecules. The NMR technique has developed very rapidly since the first commercial instrument, a Varian HR-30, was installed in 1952 at the Humble Oil Company in Baytown, Texas. In analytical chemistry, NMR is a technique that enables us to study the shape and structure of molecules. In particular, it reveals the different chemical environments of the NMR-active nuclei present in a molecule, from which the authors can ascertain the structure of the molecule. Since the 1970s, the technology associated with NMR has advanced dramatically. The theory, instrument design, and mathematics that make NMR so powerful are complex; a good understanding of quantum mechanics, physics, and electrical engineering is needed to understand modern NMR experiments.