ABSTRACT
Bioavailability of some hydrophobic bioactive like carotenoids, polyphenols, fat solvent nutrients, phytosterols (PS), and unsaturated fats are constrained due to their restricted water dissolvability, and in some occurrence chemical stability. The week bioavailability rate of such bio-actives might be because of low bio-accessibility, poor absorption, inside the gastrointestinal tract (GIT). Hydrophobic bio-actives compounds of nutraceutical’s bioavailability can be improved utilizing solid dispersion methods. These approaches are considered actual progression in beating restricted aqueous dissolvability and oral ingestion issues. This chapter features the potential systems for expanding the nutraceutical’s oral bioavailability dependent on SDs methods. Also, this chapter audits the different manufacturing procedures of SDs and gathers a portion of the ongoing innovation technology. The various sorts of SDs dependent on the molecular arrangement have been featured. A portion of the applied facts to be taken care while preparing SDs, for example, determination of carrier and strategies for physicochemical portrayal, alongside knowledge into the molecular arrangement of action of medications in SDs are discussed.
