ABSTRACT
Current development in the science of nutraceuticals aims to improve the benefits of functional foods, including minerals, vitamins, and other dietary supplements (DS). Nano-nutraceuticals actively participate in the safe and effective delivery of dietary bioactive. Recent trends in the delivery of nutraceuticals, including medical nutrition, phytonutrients, and nutrition via solid lipid nanoparticles (SLNs), have emerged since the last few decades with the objective of controlled and targeted delivery. SLNs witnesses promising alternatives for various colloidal drug and nutraceuticals delivery systems viz., nanoemulsion, liposomes, and polymeric nanoparticles. The biodegradable and biocompatible nature of SLNs proves itself favorable among other polymeric nanoparticles. Furthermore, SLNs ensure better therapeutics by modifying nutrients release kinetics, bio-distribution, and greater uptake in tissues. Despite the potential ability of SLNs for nutrient delivery, their manufacturing still poses a challenge. USFDA (United States Food and Drug Administration) in its current guidelines, made it mandatory to implement quality by design (QbD) approach for the manufacturing of pharmaceuticals. The proposed chapter presents insight on SLNs, including basic components, manufacturing techniques, characterization parameters, critical quality attributes (CQAs), and applications towards nutraceutical delivery.
