ABSTRACT
Based on literature review, the efficacy of Aloe vera has been validated for the treatment of irritable bowel syndrome. This plant has high therapeutic effects on human health due to presence of aloe-emodin, acemannan, aloeride, ethyl chromones, flavonoids, saponin, amino acids, vitamins, and minerals. Leaves containing jelly substances have been able to reduce the secretion of autacoid E2 and interleukin-18 (IL-18) in the colon tissue layer. An in vivo study shows that the extract of this plant could reduce tumor necrosis factor-α levels and the expression of IL-1ß messenger RNA.
