ABSTRACT

The medicinal plant, garlic, is used traditionally as a spice and flavoring agent and for therapeutic purposes for the management of an array of disease conditions. The literature provided scientific evidence on promising potential of garlic to treat gastrointestinal neoplasms, gastrointestinal infections and ulcers, inflammatory bowel disease, gastritis, and diarrhea of varied etiologies. This chapter identifies both experimental and epidemiological studies carried out on garlic and its bioactive compounds that justifies its use in the management of gastrointestinal disorders.

into two main groups: (1) Lipid-soluble allyl sulfur compounds (Fig. 5.1), such as, DADS (diallyl disulfide), DATS (diallyl trisulfide) and DAS (diallyl sulfur). (2) Water-soluble allyl sulfur compounds (Fig. 5.2), such as, S-allyl-cysteine and G-glutamyl-S-allyl-cysteine.