Cloud computing with Internet of Things (IoT) forms the backbones of futuristic computing technology. To avoid huge costs and to save time as well as resources, cloud computing is the best option. IoT connects the whole digital world into a single global network. The only issue is the security of data that is being stored or generated by these devices. Any breach in security may risk a huge loss of infrastructure as well as capital. The only solution that exists is enciphering data before it leaves or is stored in the system. In this chapter, a novel encryption framework has been proposed by merging the features of both symmetric as well asymmetric algorithms. Experimental results prove that the complexity of a novel approach is less and it requires less resource consumption but at the same time, it exhibits good performance and security.