ABSTRACT
In the 1990s, the zebrafish—a small fish first described in 1822 as part of the fauna of the river Ganges—became the most important model organism for vertebrate embryonic development. Several aspects predestinate this small fish for its career in laboratories all over the world: easy and cheap husbandry, with a fully sequenced genome; mating produces hundreds of eggs that can be obtained year-round; and the eggs and early embryos are transparent and develop very rapid outside the mother. Today, the zebrafish is also an important model for human diseases and their treatments. Here, we focus on several aspects of redox regulation during zebrafish development, differentiation, and regeneration, especially the function of oxidoreductases of the thioredoxin family.
