ABSTRACT
This chapter summarizes the neuropharmacological properties of coriander and its components, including their sedative, anti-anxiety, anti-depressive, anticonvulsant and anti-seizures, memory improving, anti-Parkinson's, and protective effects on neurotoxicity. The main coriander oil (EO) components are linoleic and linolenic acids. A study on the effects of ethanol extract of coriander seeds on learning in second-generation mice showed that the plant extract did not improve learning in a short period after training, while it improved learning in the long term. The coriander seeds EO from different geographical origins also showed variation in their constituents. These results showed that EO and extracts of coriander exhibit sedative and hypnotic activities in a pentobarbital-induced hypnotic model. The anti-anxiety activity of coriander leaf aqueous extract has also been evaluated in mice and compared with the effects of diazepam as a standard drug.
