ABSTRACT
Conducting polymers (CPs) have had great importance in recent years due to their miscellaneous applications in biomedical applications, for example, drug progression, biosensors, bioactuators, and as antimicrobial polymers. CPs can be synthesized through the electrochemical polymerization method, which is most effective and straightforward than traditional chemical synthesis. Polyaniline (PANI), polythiophene (PT), polypyrrole (Ppy), and polyacetylene are the most common CPs used in biomedical applications. The stability and utility of these polymers can be improved when it is prepared as composites with other fibers and polymers. PANI is insoluble in standard laboratory solvents; in this manner, it is hard to degrade; hence, it is extensively used in biomedical applications. The in-vitro antimicrobial properties of the PANI against Gram-positive, Gram-negative, and fungus can be evaluated using the agar well dissemination technique. Functionalized-PANI-based polymers have the benefit of being able to kill microorganisms in the absence of disinfectants like iodine or silver. The Ppy-coated cotton, both in the presence and absence of the deposited silver nanoparticles, shows excellent antibacterial action against Staphylococcus aureus and Escherichia coli and has low cytotoxicity. These polymers can act as “smart materials” due to their response to electrical, mechanical, and environmental simulation.
