ABSTRACT
We determined the effectiveness of the tenotomy procedure in decreasing the nystagmus of 10 selected adult subjects with CN. The primary outcome measure was the “eXpanded Nystagmus Acuity Function” (NAFX), calculated in masked fashion from eye-movement data. All subjects had persistent (one year follow-up), postoperative increases in the NAFX of their fixing (preferred) eye (average=48.8%). Secondary outcomes such as optotype visual acuity increased in 3 subjects (including 1 albino) and the NEI-VFQ showed an improvement in vision-specific mental health in all patients. There were no adverse reactions. Tenotomy caused significant damping of their CN, including aperiodic alternating nystagmus (APAN); it also changed the APAN cycle.
