ABSTRACT
The phytotoxins or plant‐derived toxins can be largely categorized as glycosides, organic acids, alkaloids, resinoid, and proteinaceous compounds. There is a major concern regarding the deleterious impact of food toxins of plant origin and the determination of the specific class of toxins. Reports on their substantial spread, as food toxins constitute a critical challenge in the investigation of parental groups and metabolites. In such cases, LC-MS-based detection and quantification provide accurate and reliable solutions. Because of the diverse nature of toxins, both low- and high-resolution mass spectrometry methods have been well studied and implemented for detection. Also, it was observed that considerable progress has been made in sample preparation strategies, sampling device employment, employing hybrid MS platforms, and the associated data analysis and interpretation. This critical chapter reviews progress in LC-MS-based detection and quantification of food toxins of plant origin while specifying key challenges and ideal suggestions for the development of more advanced LC-MS analytical systems.
