ABSTRACT

The use of radiotherapy for the treatment of non-melanoma skin cancers is well established, with data demonstrating low rates of tumor recurrence comparable to surgery, and acceptable cosmesis. In this clinical context, radiotherapy may either be delivered with superficial external beam radiotherapy, or contact brachytherapy; however, regardless of the technique chosen, some damage to healthy tissue is inevitable. This chapter presents an overview of the pathophysiology and management of potential side effects from radiotherapy for non-melanoma skin cancers, based on current best evidence. Recognized systems for scoring adverse events, along with the role of the radiation therapist and the patient in reporting and managing acute and late effects are discussed.