ABSTRACT
This chapter discusses two rare groups of skin neoplasms. Primary cutaneous lymphomas encompass different subtypes of lymphoma, most often T cell lymphomas. They have a much more indolent clinical course compared to similar subtypes in lymph nodes or other organs, and they are usually treated with skin-directed therapies. Only some aggressive subtypes and disseminated disease are treated up front with systemic therapy. Cutaneous lymphomas are highly radiosensitive, and radiotherapy offers an effective treatment for local control when patients no longer respond satisfactorily to dermatologic treatments. Special radiotherapy techniques, in particular total skin electron beam therapy, are discussed.
Cutaneous sarcomas are generally radiation resistant. Their primary management is primarily surgical. The role of radiotherapy in curative, adjuvant and palliative settings is described.
