Today, e-health and online visits are an alternative to in-person visits to continue addressing patients’ ambulatory treatment needs following the COVID-19 pandemic and its imposed social distancing rules. Enhanced by the COVID-19 “new normal,” telemedicine is becoming more and more common in many healthcare fields, including oncology and pain medicine. While the outcome seems optimistic, clinicians and patients are required to find and experiment with new ways of translating, transferring, and sharing knowledge.

This chapter uses a case study methodology, investigating a program recently initiated by the National Cancer Institute of Aviano, Italy, named “Doctor @ Home” (D@H).

Although telemedicine is currently being largely investigated by the international clinical and management literature, several research gaps emerge. The chapter deepens the topic of knowledge translation, transfer, and sharing in a new context, that of telehealth. The co-production of the treatment and the co-learning approach constitute the core building blocks of the telemedicine program. Several tools are identified as facilitators of such a process, opening up to new perspectives for knowledge management in the healthcare sector.

The preliminary insights into an emerging telemedicine program are presented in the chapter. Other healthcare organizations can readily repeat D@H’s mechanism and procedures to boost clinical outcomes.