ABSTRACT
For the last few decades, nanocarrier strategies have endeavored to cause a revolution in the diagnostic and therapeutic domain due to the miniature dimensions of nanoparticles, inflated surface area to volume ratio, improved solubility, and other beneficial attributes of the system. Among a large number of encapsulating materials, phospholipid has been appraised as one of the most fascinating and multi-faceted natural excipients in the nanocarrier platform because of its inherent biocompatibility, promising biodegradability, minimal cytotoxicity, plentiful renewable sources, clinically useful site-specific targeting, and systematized uptake. Chapter 8 primarily concentrates on the newest advancements of phospholipid-based nanovehicles to deliver a substantial number of therapeutics. The numerous aspects of fabrication, obstacles, in vivo and in vitro bioactivity investigations, the divergence in the release kinetics, as well as the molecular interactions between the bioactive core and the phospholipid-based nanostructures are discussed here to probe the upcoming possibilities of this relatively unprecedented strategy.
Graphical Abstract: Phospholipid-based nanoplatform: Exploring several delivery tools for therapeutic intervention
