ABSTRACT
The emergence of nanotechnology has led to immense research in nanoparticle-based therapeutics that offer superior bioavailability, efficacy, and targeted delivery. Multiple attempts have been made in the past decade to harness and utilize the beneficial effects of nanoparticle drug delivery systems (DDS) in patient care. Innovations in the field have led to the emergence of nanoparticle and nutraceutical conjugates resulting in multifunctional nano-nutraceutical DDS for disease treatment. However, preclinical and clinical data suggest that these systems, although beneficial, possess a propensity for causing acute toxicity if over-utilized. Chapter 9 addresses these concerns and provides a detailed investigation of the impact, scope, and potential benefits of nano-nutraceuticals for therapy in neurodegenerative diseases, management of cancer, and oxidative stress. Concerns pertaining to safety and suggestions to bridge research gaps and to improve patient acceptability have also been discussed.
