ABSTRACT

The amphiphilic molecules produced by microorganisms (prokaryotes and eukaryotes) are termed as biosurfactants. Among the different types i.e., glycolipids, lipopeptides, phospholipids and polymeric biosurfactants, lipopeptide biosurfactants have gained attention due to low production cost, simplicity in downstream processing and versatile utilisation. They are produced by Bacillus sp. which are ubiquitously present in varied environments such as soil, air and aqua. These lipopeptides have proven their mantle in agriculture, bioremediation and health sciences. Their commercial use and market are also vast due to promising outcomes while meeting a challenge. The current chapter gives an overview about the Bacillus lipopeptides, influence of quorum sensing (QS) in their production and applications in agriculture, bioremediation and health with a note on clustered regularly interspaced short palindromic repeats interference (CRISPRi) technology in enhancement of surfactin lipopeptide production.