ABSTRACT

Recently, the use of metabolites in diagnostic tools is increasing. Some metabolites are biomarkers for various diseases that affect humans; thus, their detection and quantification are important. The detection of metabolites is also essential in the food industry, forensic investigation, and drug discovery. In recent years, the application of nanocomposites has exploded. During this time, conducting polymers have attracted tremendous attention due to their impressive electrical, magnetic, thermal, and mechanical properties. This chapter discusses advances in conducting polymers for qualitative and quantitative electrochemical analysis of metabolites. This includes the types of conducting polymers, their synthesis, and properties. Also, the application of conducting polymer to detect drugs and their metabolites is covered. Furthermore, the detection of intrinsic biological metabolites such as functional biomolecules, biomarkers, and cellular by-products as well as food toxins using conducting polymers and their composites are discussed. Finally, this chapter concludes with the benefits, challenges, and prospects of conducting polymers in the sustainable development of biosensors.