ABSTRACT

Biomarkers are the biological molecules that play role in the detection of disease and its severity. Biomarkers hold promise for personalized medicine because of their clinical and pathological significance. Biomarkers are also used to discover drugs and monitor the therapeutic effects on the patient. High throughput technologies, radio-labeled techniques, electrochemical sensors, microfluidic devices, and spectroscopic techniques are used nowadays for the early detection of biomarkers. These detection methodologies for biomarkers identification from biologically complex mediums have their respective characteristics. The innovative electronic methods for biomarker identification are sensitive, specific, and reproducible. The early and accurate detection of biomarkers subsequently predicts the treatment response, reduces the trial-and-error switches of medications, and facilitates the discovery of effective therapeutic approaches.