ABSTRACT
Antimicrobial resistance in wastewater can be used as an early indicator for health risk assessment. The present study depicts the antimicrobial sensitivity profile of three indigenous pathogens previously isolated from sanitary landfill in order to assess their environmental and human health hazard potential.Three indigenous pathogens isolated in our previous study, Leclercia adecarboxylata MT186162, Pseudescherichia vulneris MT186163, and Brucella inopinata MT186164 were used for the present study. Antibiotic sensitivity was tested against 16 different antibiotics belonging to eight different classes, viz. carbapenem, β-lactams, cyclin, cephalosporins, etc., and reported in the form of Multi-Drug Resistance MDR and Multiple Antibiotic Resistance MAR Index. Results showed that all the isolates showed varied responses to different tested antibiotics. The highest MDR against eight antibiotics was observed for Brucella inopinata followed by Leclercia adecarboxylata (5) and Pseudescherichia vulneris (2). Multiple Antibiotic Resistance Index revealed Pseudescherichia vulneris and Brucella inopinata, to be resistant strains and hence may be monitored as an indicator pathogen in leachate. Hence we can conclude that pathogens isolated from sanitary landfill showed potentially high antibiotic resistance, and their presence, as well as concentration, should be carefully monitored while recycling leachate into the environment so as to lower the human health risk and maintain environmental sustainability.
