ABSTRACT

Cannabis sativa is a potent pharmaceutically important medicinal plant that produces approximately 500 compounds and around 113 cannabinoids. In the Indian traditional medicine system, C. sativa has been used as a hypnotic, sedative, hallucinogenic, analgesic, and anti-inflammatory agent. Various microbial communities are associated with this plant contributing to its growth, resistance against pathogens, mineral nutrient uptake and production of plant secondary metabolites. Researchers are paying attention to investigating the major role of mutual partnership between plants and microbes to increase the production of metabolites. Therefore, there is a need to explore the clear role of endophytes in the plant. This chapter aims to summarize the relation between endophytic microbial communities and host Cannabis sativa.