ABSTRACT

Persistent organic pollutants (POPs) are a worldwide concern due to their bioaccumulative nature and persistence for a long period of time, resulting in large-scale environmental contamination. These pollutants are extremely resistant to biodegradation and subject to transfer over long distances via the atmosphere. They may be present even in regions with no historical use. POPs can bioaccumulate in adipose tissue due to their lipophilicity and can seriously affect the nervous, hepatic, reproductive, and hormonal systems of the contaminated organisms, including plants, animals, and humans. Therefore, they are responsible for various lethal diseases and environmental problems. The diversity of diseases due to POPs includes diabetes, endocrine disorders, cancer, and cardiovascular, and reproductive problems. As to achieve sustainability and safety in relation to the integrity 4of public and environmental health, monitoring the effects of POPs and taking measures to mitigate the negative consequences is imperative.